Plastin 1 drives metastasis of colorectal cancer through the IQGAP1/Rac1/ERK pathway

Tumor metastasis is the dominant cause of death in colorectal cancer (CRC) patients, and it often involves dysregulation of various cytoskeletal proteins. Plastin 1 (PLS1) is an actin‐bundling protein that has been implicated in the structure of intestinal epithelial microvilli; however, its role in...

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Vydáno v:Cancer Sci
Hlavní autoři: Zhang, Tongtong, Wang, Zheng, Liu, Yanjun, Huo, Yongxu, Liu, Hongtao, Xu, Chenxin, Mao, Rui, Zhu, Yifang, Liu, Lei, Wei, Danfeng, Liu, Guanzhi, Pan, Biran, Tang, Yan, Zhou, Zheng, Yang, Chunlei, Guo, Yuanbiao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419044/
https://ncbi.nlm.nih.gov/pubmed/32350953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14438
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