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Advances in oligonucleotide drug delivery
Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these molecules have potential therapeutic applicat...
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| Publicado en: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7419031/ https://ncbi.nlm.nih.gov/pubmed/32782413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-0075-7 |
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