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Two Stage Designs for Phase III Clinical Trials

Phase III platform trials are increasingly used to evaluate a sequence of treatments for a specific disease. Traditional approaches to structure such trials tend to focus on the sequential questions rather than the performance of the entire enterprise. We consider two-stage trials where an early eva...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:medRxiv
Prif Awduron: Follmann, Dean, Proschan, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418751/
https://ncbi.nlm.nih.gov/pubmed/32793927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.29.20164525
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