Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement

BACKGROUND: Chronic exposure to inorganic arsenic (iAs) is a significant public health problem. Methylation of iAs by arsenic methyltransferase (AS3MT) controls iAs detoxification and modifies risks of iAs-induced diseases. Mechanisms underlying these diseases have been extensively studied using ani...

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Bibliografski detalji
Izdano u:Environ Health Perspect
Glavni autori: Koller, Beverly H., Snouwaert, John N., Douillet, Christelle, Jania, Leigh A., El-Masri, Hisham, Thomas, David J., Stýblo, Miroslav
Format: Artigo
Jezik:Inglês
Izdano: Environmental Health Perspectives 2020
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418654/
https://ncbi.nlm.nih.gov/pubmed/32779937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP6943
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