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A Surface Loop Modulates Activity of the Bacillus Class D β-Lactamases

The expression of β-lactamases is a major mechanism of bacterial resistance to the β-lactam antibiotics. Four molecular classes of β-lactamases have been described (A, B, C and D), however until recently the class D enzymes were thought to exist only in Gram-negative bacteria. In the last few years,...

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Vydáno v:J Struct Biol
Hlavní autoři: Stewart, Nichole K., Bhattacharya, Monolekha, Toth, Marta, Smith, Clyde A., Vakulenko, Sergei B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418532/
https://ncbi.nlm.nih.gov/pubmed/32512156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107544
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