GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ

BACKGROUND: The granulocyte-macrophage colony-stimulating factor (GM-CSF) (or CSF-2) is involved in myeloid cell growth and differentiation, and, possibly, a major mediator of inflammation in body tissues. The role of GM-CSF in the activation of microglia (CNS resident macrophages) and the consequen...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Dikmen, Hasan Onur, Hemmerich, Marc, Lewen, Andrea, Hollnagel, Jan-Oliver, Chausse, Bruno, Kann, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418331/
https://ncbi.nlm.nih.gov/pubmed/32782006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01903-4
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