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p21-Activated Kinases in Thyroid Cancer

The family of p21-activated kinases (PAKs) are oncogenic proteins that regulate critical cellular functions. PAKs play central signaling roles in the integrin/CDC42/Rho, ERK/MAPK, PI3K/AKT, NF-κB, and Wnt/β-catenin pathways, functioning both as kinases and scaffolds to regulate cell motility, mitosi...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Bautista, Luis, Knippler, Christina M, Ringel, Matthew D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417880/
https://ncbi.nlm.nih.gov/pubmed/32609833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa105
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