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Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches

Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pathway modeling can become a real nightmare for researchers,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lo-Thong, Ophélie, Charton, Philippe, Cadet, Xavier F., Grondin-Perez, Brigitte, Saavedra, Emma, Damour, Cédric, Cadet, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417601/
https://ncbi.nlm.nih.gov/pubmed/32778715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70295-5
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