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Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches

Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pathway modeling can become a real nightmare for researchers,...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lo-Thong, Ophélie, Charton, Philippe, Cadet, Xavier F., Grondin-Perez, Brigitte, Saavedra, Emma, Damour, Cédric, Cadet, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417601/
https://ncbi.nlm.nih.gov/pubmed/32778715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70295-5
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