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Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches

Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pathway modeling can become a real nightmare for researchers,...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Lo-Thong, Ophélie, Charton, Philippe, Cadet, Xavier F., Grondin-Perez, Brigitte, Saavedra, Emma, Damour, Cédric, Cadet, Frédéric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417601/
https://ncbi.nlm.nih.gov/pubmed/32778715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70295-5
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