Cosmc controls B cell homing

The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, and the consequent decrease of protein O-glycosylation, induces developmental blocks of mouse B cells. After transfer into wil...

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Pubblicato in:Nat Commun
Autori principali: Zeng, Junwei, Eljalby, Mahmoud, Aryal, Rajindra P., Lehoux, Sylvain, Stavenhagen, Kathrin, Kudelka, Matthew R., Wang, Yingchun, Wang, Jianmei, Ju, Tongzhong, von Andrian, Ulrich H., Cummings, Richard D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417590/
https://ncbi.nlm.nih.gov/pubmed/32778659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17765-6
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