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The Endoplasmic Reticulum Chaperone Cosmc Directly Promotes in Vitro Folding of T-synthase
The T-synthase is the key β3-galactosyltransferase essential for biosynthesis of core 1 O-glycans (Galβ1–3GalNAcα1-Ser/Thr) in animal cell glycoproteins. Here we describe the novel ability of an endoplasmic reticulum-localized molecular chaperone termed Cosmc to specifically interact with partly den...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807302/ https://ncbi.nlm.nih.gov/pubmed/19923218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065169 |
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