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The Endoplasmic Reticulum Chaperone Cosmc Directly Promotes in Vitro Folding of T-synthase

The T-synthase is the key β3-galactosyltransferase essential for biosynthesis of core 1 O-glycans (Galβ1–3GalNAcα1-Ser/Thr) in animal cell glycoproteins. Here we describe the novel ability of an endoplasmic reticulum-localized molecular chaperone termed Cosmc to specifically interact with partly den...

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Bibliographische Detailangaben
Hauptverfasser: Aryal, Rajindra P., Ju, Tongzhong, Cummings, Richard D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807302/
https://ncbi.nlm.nih.gov/pubmed/19923218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065169
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