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De novo sequence assembly requires bioinformatic checking of chimeric sequences

De novo assembly of sequence reads from next generation sequencing platforms is a common strategy for detecting presence and sequencing of viruses in biospecimens. Amplification artifacts and presence of several related viruses in the same specimen can lead to assembly of erroneous, chimeric sequenc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arroyo Mühr, Laila Sara, Lagheden, Camilla, Hassan, Sadaf Sakina, Kleppe, Sara Nordqvist, Hultin, Emilie, Dillner, Joakim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417191/
https://ncbi.nlm.nih.gov/pubmed/32777809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237455
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