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De novo sequence assembly requires bioinformatic checking of chimeric sequences
De novo assembly of sequence reads from next generation sequencing platforms is a common strategy for detecting presence and sequencing of viruses in biospecimens. Amplification artifacts and presence of several related viruses in the same specimen can lead to assembly of erroneous, chimeric sequenc...
Enregistré dans:
| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7417191/ https://ncbi.nlm.nih.gov/pubmed/32777809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237455 |
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