Functional Dissection of a Viral DNA Packaging Machine’s Walker B Motif

Many viruses employ ATP-powered motors for genome packaging. We combined genetic, biochemical, and single-molecule techniques to confirm the predicted Walker-B ATP-binding motif in the phage λ motor and to investigate the roles of the conserved residues. Most changes of the conserved hydrophobic res...

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Bibliografiska uppgifter
I publikationen:J Mol Biol
Huvudupphovsmän: delToro, Damian, Ortiz, David, Ordyan, Mariam, Pajak, Joshua, Sippy, Jean, Catala, Alexis, Oh, Choon-Seok, Vu, Amber, Arya, Gaurav, Smith, Douglas E., Catalano, Carlos E., Feiss, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416571/
https://ncbi.nlm.nih.gov/pubmed/31473160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.08.012
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