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DnaB helicase is recruited to the replication initiation complex via binding of DnaA domain I to the lateral surface of the DnaB N-terminal domain

The DNA replication protein DnaA in Escherichia coli constructs higher-order complexes on the origin, oriC, to unwind this region. DnaB helicase is loaded onto unwound oriC via interactions with the DnaC loader and the DnaA complex. The DnaB–DnaC complex is recruited to the DnaA complex via stable b...

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Foilsithe in:J Biol Chem
Main Authors: Hayashi, Chihiro, Miyazaki, Erika, Ozaki, Shogo, Abe, Yoshito, Katayama, Tsutomu
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415982/
https://ncbi.nlm.nih.gov/pubmed/32540966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014235
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