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Highly organized DnaA–oriC complexes recruit the single-stranded DNA for replication initiation
In Escherichia coli, the replication origin oriC consists of two functional regions: the duplex unwinding element (DUE) and its flanking DnaA-assembly region (DAR). ATP-DnaA molecules multimerize on DAR, unwinding DUE for DnaB helicase loading. However, DUE-unwinding mechanisms and functional struct...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287180/ https://ncbi.nlm.nih.gov/pubmed/22053082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr832 |
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