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Protein docking and steered molecular dynamics suggest alternative phospholamban-binding sites on the SERCA calcium transporter
The transport activity of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in cardiac myocytes is modulated by an inhibitory interaction with a transmembrane peptide, phospholamban (PLB). Previous biochemical studies have revealed that PLB interacts with a specific inhibitory site on SERCA, a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415981/ https://ncbi.nlm.nih.gov/pubmed/32554805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012948 |
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