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Phospholamban C-terminal Residues Are Critical Determinants of the Structure and Function of the Calcium ATPase Regulatory Complex

To determine the structural and regulatory role of the C-terminal residues of phospholamban (PLB) in the membranes of living cells, we fused fluorescent protein tags to PLB and sarco/endoplasmic reticulum calcium ATPase (SERCA). Alanine substitution of PLB C-terminal residues significantly altered f...

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Detalhes bibliográficos
Main Authors: Abrol, Neha, Smolin, Nikolai, Armanious, Gareth, Ceholski, Delaine K., Trieber, Catharine A., Young, Howard S., Robia, Seth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162186/
https://ncbi.nlm.nih.gov/pubmed/25074938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562579
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