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Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump
Phospholamban physically interacts with the sarcoplasmic reticulum calcium pump (SERCA) and regulates contractility of the heart in response to adrenergic stimuli. We have studied this interaction using electron microscopy of two-dimensional crystals of SERCA in complex with phospholamban. In previo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121535/ https://ncbi.nlm.nih.gov/pubmed/21108950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.014 |
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