Loading...

Radiotherapy cooperates with IL15 to induce antitumor immune responses

Focal radiotherapy can promote cross-presentation of tumor antigens to T cells, but by itself it is insufficient to induce therapeutically effective T-cell responses. The common gamma-chain cytokine IL15 promotes and sustains the proliferation and effector function of CD8(+) T cells, but has limited...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Immunol Res
Main Authors: Pilones, Karsten A., Charpentier, Maud, Garcia-Martinez, Elena, Daviaud, Camille, Kraynak, Jeffrey, Aryankalayil, Joseph, Formenti, Silvia C., Demaria, Sandra
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415682/
https://ncbi.nlm.nih.gov/pubmed/32532811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0338
Tags: Add Tag
No Tags, Be the first to tag this record!