Intravital imaging reveals motility of adult hematopoietic stem cells in the bone marrow niche

Adult mammalian hematopoietic stem cells (HSCs) reside in the bone marrow (BM) but can be mobilized into blood for use in transplantation. HSCs interact with BM niche cells producing growth factor c-Kit ligand (Kitl/SCF) and chemokine CXCL12, and were thought to be static and sessile. We used two-ph...

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Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Upadhaya, Samik, Krichevsky, Oleg, Akhmetzyanova, Ilseyar, Sawai, Catherine M., Fooksman, David R., Reizis, Boris
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415613/
https://ncbi.nlm.nih.gov/pubmed/32589864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.06.003
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