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Intravital imaging reveals motility of adult hematopoietic stem cells in the bone marrow niche
Adult mammalian hematopoietic stem cells (HSCs) reside in the bone marrow (BM) but can be mobilized into blood for use in transplantation. HSCs interact with BM niche cells producing growth factor c-Kit ligand (Kitl/SCF) and chemokine CXCL12, and were thought to be static and sessile. We used two-ph...
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| Veröffentlicht in: | Cell Stem Cell |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415613/ https://ncbi.nlm.nih.gov/pubmed/32589864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.06.003 |
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