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Intravital imaging reveals motility of adult hematopoietic stem cells in the bone marrow niche

Adult mammalian hematopoietic stem cells (HSCs) reside in the bone marrow (BM) but can be mobilized into blood for use in transplantation. HSCs interact with BM niche cells producing growth factor c-Kit ligand (Kitl/SCF) and chemokine CXCL12, and were thought to be static and sessile. We used two-ph...

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Detalles Bibliográficos
Publicado en:Cell Stem Cell
Main Authors: Upadhaya, Samik, Krichevsky, Oleg, Akhmetzyanova, Ilseyar, Sawai, Catherine M., Fooksman, David R., Reizis, Boris
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415613/
https://ncbi.nlm.nih.gov/pubmed/32589864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.06.003
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