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Enhanced expression of catalase in mitochondria modulates NF-κB dependent lung inflammation through alteration of metabolic activity in macrophages
NF-κB is a redox sensitive transcription factor that plays a key role in regulating the immune response. In these studies, we intended to investigate the role of mitochondrial-derived reactive oxygen species (ROS) in regulating NF-κB activation by studying transgenic mice that over-express mitochond...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415609/ https://ncbi.nlm.nih.gov/pubmed/32601098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900820 |
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