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Epithelial NF-κB activation promotes urethane-induced lung carcinogenesis

Chronic inflammation is linked to carcinogenesis in several organ systems. In the lungs, NF-κB, a central effector of inflammatory responses, is frequently activated in non-small-cell lung cancer, but its role in tumor promotion has not been studied. Several lines of evidence indicate that ethyl car...

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Detalhes bibliográficos
Main Authors: Stathopoulos, Georgios T., Sherrill, Taylor P., Cheng, Dong-Sheng, Scoggins, Robert M., Han, Wei, Polosukhin, Vasiliy V., Connelly, Linda, Yull, Fiona E., Fingleton, Barbara, Blackwell, Timothy S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141808/
https://ncbi.nlm.nih.gov/pubmed/18000061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705316104
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