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Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukemia and promotes survival through Mcl-1
Sphingolipid metabolism is increasingly recognized as a therapeutic target in cancer due to its regulation of cell proliferation and apoptosis. The sphingolipid rheostat is proposed to control cell fate through maintaining balance between pro-apoptotic and pro-survival sphingolipids. This balance is...
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| 出版年: | Br J Haematol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415522/ https://ncbi.nlm.nih.gov/pubmed/32124438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.16530 |
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