Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells

The high recurrence rates of colorectal cancer have been associated with a small population of cancer stem cells (CSCs) that are resistant to the standard chemotherapeutic drug, 5-fluorouracil (5FU). Thymoquinone (TQ) has shown promising antitumor properties on numerous cancer systems both in vitro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ballout, Farah, Monzer, Alissar, Fatfat, Maamoun, Ouweini, Hala El, Jaffa, Miran A., Abdel-Samad, Rana, Darwiche, Nadine, Abou-Kheir, Wassim, Gali-Muhtasib, Hala
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415406/
https://ncbi.nlm.nih.gov/pubmed/32821342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27426
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