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Parainfluenza virus 5 fusion protein maintains pre-fusion stability but not fusogenic activity following mutation of a transmembrane leucine/isoleucine domain

The paramyxoviruses Hendra virus (HeV) and parainfluenza virus 5 (PIV5) require the fusion (F) protein to efficiently infect cells. For fusion to occur, F undergoes dramatic, essentially irreversible conformational changes to merge the viral and cell membranes into a continuous bilayer. Recently, a...

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Bibliografiska uppgifter
I publikationen:J Gen Virol
Huvudupphovsmän: Branttie, Jean Mawuena, Dutch, Rebecca Ellis
Materialtyp: Artigo
Språk:Inglês
Publicerad: Microbiology Society 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414451/
https://ncbi.nlm.nih.gov/pubmed/32100701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001399
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