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Transmembrane Domain Dissociation Is Required for Hendra Virus F Protein Fusogenic Activity

Hendra virus (HeV) is a zoonotic paramyxovirus that utilizes a trimeric fusion (F) protein within its lipid bilayer to mediate membrane merger with a cell membrane for entry. Previous HeV F studies showed that transmembrane domain (TMD) interactions are important for stabilizing the prefusion confor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Slaughter, Kerri Beth, Dutch, Rebecca Ellis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819933/
https://ncbi.nlm.nih.gov/pubmed/31462574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01069-19
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