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Transmembrane Domain Dissociation Is Required for Hendra Virus F Protein Fusogenic Activity
Hendra virus (HeV) is a zoonotic paramyxovirus that utilizes a trimeric fusion (F) protein within its lipid bilayer to mediate membrane merger with a cell membrane for entry. Previous HeV F studies showed that transmembrane domain (TMD) interactions are important for stabilizing the prefusion confor...
Enregistré dans:
| Publié dans: | J Virol |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6819933/ https://ncbi.nlm.nih.gov/pubmed/31462574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01069-19 |
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