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Side Chain Packing below the Fusion Peptide Strongly Modulates Triggering of the Hendra Virus F Protein

Triggering of the Hendra virus fusion (F) protein is required to initiate the conformational changes which drive membrane fusion, but the factors which control triggering remain poorly understood. Mutation of a histidine predicted to lie near the fusion peptide to alanine greatly reduced fusion desp...

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Detalhes bibliográficos
Main Authors: Smith, Everett Clinton, Dutch, Rebecca Ellis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950584/
https://ncbi.nlm.nih.gov/pubmed/20702638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01108-10
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