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A Hydrophobic Target: Using the Paramyxovirus Fusion Protein Transmembrane Domain To Modulate Fusion Protein Stability

Enveloped viruses utilize surface glycoproteins to bind and fuse with a target cell membrane. The zoonotic Hendra virus (HeV), a member of the family Paramyxoviridae, utilizes the attachment protein (G) and the fusion protein (F) to perform these critical functions. Upon triggering, the trimeric F p...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Barrett, Chelsea T., Webb, Stacy R., Dutch, Rebecca Ellis
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694835/
https://ncbi.nlm.nih.gov/pubmed/31217248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00863-19
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