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West Nile Virus fidelity modulates the capacity for host cycling and adaptation

The fidelity of flaviviruses is thought to be tightly regulated for optimal fitness within and between hosts. West Nile virus (WNV) high-fidelity (HiFi) mutations V793I and G806R within the RNA-dependent RNA polymerase, and low-fidelity (LoFi) mutation T248I within the methyltransferase, were previo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Virol
Prif Awduron: Caldwell, Haley S., Ngo, Kiet, Pata, Janice D., Kramer, Laura D., Ciota, Alexander T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Microbiology Society 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414436/
https://ncbi.nlm.nih.gov/pubmed/32068528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001393
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