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Divergent Mutational Landscapes of Consensus and Minority Genotypes of West Nile Virus Demonstrate Host and Gene-Specific Evolutionary Pressures

Our current understanding of the natural evolution of RNA viruses comes largely from consensus level genetic analyses which ignore the diverse mutant swarms that comprise within-host viral populations. The breadth and composition of viral mutant swarms impact viral fitness and adaptation, and the ca...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Caldwell, Haley S., Lasek-Nesselquist, Erica, Follano, Paisley, Kramer, Laura D., Ciota, Alexander T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692055/
https://ncbi.nlm.nih.gov/pubmed/33143358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111299
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