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2’-Fluoro-2’-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705

Noroviruses are the main causative agents of acute viral gastroenteritis worldwide. However, no vaccine or specific antiviral treatment is available, imposing a heavy global health burden. The nucleoside analogue 2’-fluoro-2’-deoxycytidine (2’-FdC) has been reported to have broad antiviral activity....

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Detalhes bibliográficos
Publicado no:Arch Virol
Main Authors: Yu, Peifa, Wang, Yining, Li, Yunlong, Li, Yang, Miao, Zhijiang, Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414258/
https://ncbi.nlm.nih.gov/pubmed/32770483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-020-04759-4
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