2’-Fluoro-2’-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705

Noroviruses are the main causative agents of acute viral gastroenteritis worldwide. However, no vaccine or specific antiviral treatment is available, imposing a heavy global health burden. The nucleoside analogue 2’-fluoro-2’-deoxycytidine (2’-FdC) has been reported to have broad antiviral activity....

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Bibliographic Details
Published in:Arch Virol
Main Authors: Yu, Peifa, Wang, Yining, Li, Yunlong, Li, Yang, Miao, Zhijiang, Peppelenbosch, Maikel P., Pan, Qiuwei
Format: Artigo
Language:Inglês
Published: Springer Vienna 2020
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414258/
https://ncbi.nlm.nih.gov/pubmed/32770483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-020-04759-4
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