Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7

Noroviruses are the main causative agents of acute viral gastroenteritis, but the host factors that restrict their replication remain poorly identified. Guanylate-binding proteins (GBPs) are interferon (IFN)-inducible GTPases that exert broad antiviral activity and are important mediators of host de...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Yu, Peifa, Li, Yang, Li, Yunlong, Miao, Zhijiang, Peppelenbosch, Maikel P., Pan, Qiuwei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278355/
https://ncbi.nlm.nih.gov/pubmed/32354743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013544
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