Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7

Noroviruses are the main causative agents of acute viral gastroenteritis, but the host factors that restrict their replication remain poorly identified. Guanylate-binding proteins (GBPs) are interferon (IFN)-inducible GTPases that exert broad antiviral activity and are important mediators of host de...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Yu, Peifa, Li, Yang, Li, Yunlong, Miao, Zhijiang, Peppelenbosch, Maikel P., Pan, Qiuwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278355/
https://ncbi.nlm.nih.gov/pubmed/32354743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013544
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