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Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation

Once described as mere “bags of enzymes,” bacterial cells are in fact highly organized, with many macromolecules exhibiting nonuniform localization patterns. Yet the physical and biochemical mechanisms that govern this spatial heterogeneity remain largely unknown. Here, we identify liquid–liquid pha...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ladouceur, Anne-Marie, Parmar, Baljyot Singh, Biedzinski, Stefan, Wall, James, Tope, S. Graydon, Cohn, David, Kim, Albright, Soubry, Nicolas, Reyes-Lamothe, Rodrigo, Weber, Stephanie C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414142/
https://ncbi.nlm.nih.gov/pubmed/32675239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005019117
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