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Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation

Once described as mere “bags of enzymes,” bacterial cells are in fact highly organized, with many macromolecules exhibiting nonuniform localization patterns. Yet the physical and biochemical mechanisms that govern this spatial heterogeneity remain largely unknown. Here, we identify liquid–liquid pha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ladouceur, Anne-Marie, Parmar, Baljyot Singh, Biedzinski, Stefan, Wall, James, Tope, S. Graydon, Cohn, David, Kim, Albright, Soubry, Nicolas, Reyes-Lamothe, Rodrigo, Weber, Stephanie C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414142/
https://ncbi.nlm.nih.gov/pubmed/32675239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005019117
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