Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation

Once described as mere “bags of enzymes,” bacterial cells are in fact highly organized, with many macromolecules exhibiting nonuniform localization patterns. Yet the physical and biochemical mechanisms that govern this spatial heterogeneity remain largely unknown. Here, we identify liquid–liquid pha...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ladouceur, Anne-Marie, Parmar, Baljyot Singh, Biedzinski, Stefan, Wall, James, Tope, S. Graydon, Cohn, David, Kim, Albright, Soubry, Nicolas, Reyes-Lamothe, Rodrigo, Weber, Stephanie C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414142/
https://ncbi.nlm.nih.gov/pubmed/32675239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005019117
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