Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice

Recent genome-wide association studies have revealed some genetic loci associated with serum uric acid levels and susceptibility to gout/hyperuricemia which contain potential candidates of physiologically important urate transporters. One of these novel loci is located upstream of SGK1 and SLC2A12,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Toyoda, Yu, Takada, Tappei, Miyata, Hiroshi, Matsuo, Hirotaka, Kassai, Hidetoshi, Nakao, Kazuki, Nakatochi, Masahiro, Kawamura, Yusuke, Shimizu, Seiko, Shinomiya, Nariyoshi, Ichida, Kimiyoshi, Hosoyamada, Makoto, Aiba, Atsu, Suzuki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414087/
https://ncbi.nlm.nih.gov/pubmed/32690690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006958117
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