Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

To clarify the physiological and pathophysiological roles of intestinal urate excretion via ABCG2 in humans, we genotyped ABCG2 dysfunctional common variants, Q126X (rs72552713) and Q141K (rs2231142), in end-stage renal disease (hemodialysis) and acute gastroenteritis patients, respectively. ABCG2 d...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Matsuo, Hirotaka, Tsunoda, Tomoyuki, Ooyama, Keiko, Sakiyama, Masayuki, Sogo, Tsuyoshi, Takada, Tappei, Nakashima, Akio, Nakayama, Akiyoshi, Kawaguchi, Makoto, Higashino, Toshihide, Wakai, Kenji, Ooyama, Hiroshi, Hokari, Ryota, Suzuki, Hiroshi, Ichida, Kimiyoshi, Inui, Ayano, Fujimori, Shin, Shinomiya, Nariyoshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004129/
https://ncbi.nlm.nih.gov/pubmed/27571712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31003
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