Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

To clarify the physiological and pathophysiological roles of intestinal urate excretion via ABCG2 in humans, we genotyped ABCG2 dysfunctional common variants, Q126X (rs72552713) and Q141K (rs2231142), in end-stage renal disease (hemodialysis) and acute gastroenteritis patients, respectively. ABCG2 d...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Matsuo, Hirotaka, Tsunoda, Tomoyuki, Ooyama, Keiko, Sakiyama, Masayuki, Sogo, Tsuyoshi, Takada, Tappei, Nakashima, Akio, Nakayama, Akiyoshi, Kawaguchi, Makoto, Higashino, Toshihide, Wakai, Kenji, Ooyama, Hiroshi, Hokari, Ryota, Suzuki, Hiroshi, Ichida, Kimiyoshi, Inui, Ayano, Fujimori, Shin, Shinomiya, Nariyoshi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004129/
https://ncbi.nlm.nih.gov/pubmed/27571712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31003
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