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Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T(H)17 responses

The current paradigm that subunit vaccines require adjuvants to optimally activate innate immunity implies that increased vaccine reactogenicity will invariably be linked to improved immunogenicity. Countering this paradigm, nanoparticulate vaccines have been reported to act as delivery systems for...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Si, Youhui, Tian, Qiaomu, Zhao, Fan, Kelly, Sean H., Shores, Lucas S., Camacho, Daniel F., Sperling, Anne I., Andrade, Michael S., Collier, Joel H., Chong, Anita S.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413739/
https://ncbi.nlm.nih.gov/pubmed/32821819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba0995
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