Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T(H)17 responses

The current paradigm that subunit vaccines require adjuvants to optimally activate innate immunity implies that increased vaccine reactogenicity will invariably be linked to improved immunogenicity. Countering this paradigm, nanoparticulate vaccines have been reported to act as delivery systems for...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Si, Youhui, Tian, Qiaomu, Zhao, Fan, Kelly, Sean H., Shores, Lucas S., Camacho, Daniel F., Sperling, Anne I., Andrade, Michael S., Collier, Joel H., Chong, Anita S.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413739/
https://ncbi.nlm.nih.gov/pubmed/32821819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba0995
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