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Trimetazidine improves hepatic lipogenesis and steatosis in non-alcoholic fatty liver disease via AMPK-ChREBP pathway

Clinical studies have demonstrated that trimetazidine (TMZ) possesses a synergistic hypolipidemic effect together with statins, but the underlying mechanism remains to be elucidated. The present study aimed to investigate the role of TMZ in non-alcoholic fatty liver disease (NAFLD). By investigating...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhang, Ying, Li, Can, Li, Xiuqi, Wu, Cheng, Zhou, Haiyan, Lu, Shuang, Liu, Xingde
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411376/
https://ncbi.nlm.nih.gov/pubmed/32705195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11309
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