Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts

Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take advantage of a transparent embryonic zebrafish xenograft model (eZXM) to visualize and track metastatic cells in real time using selective plane illumination microscopy (SPIM) for u...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Asokan, Nandini, Daetwyler, Stephan, Bernas, Stefanie N., Schmied, Christopher, Vogler, Steffen, Lambert, Katrin, Wobus, Manja, Wermke, Martin, Kempermann, Gerd, Huisken, Jan, Brand, Michael, Bornhäuser, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411039/
https://ncbi.nlm.nih.gov/pubmed/32764590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69956-2
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