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Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus
The hypothalamus plays a critical role in controlling energy balance. High-fat diet (HFD) feeding increases the gene expression of proinflammatory mediators and decreases insulin actions in the hypothalamus. Here, we show that a gut-derived hormone, glucose-dependent insulinotropic polypeptide (GIP)...
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| Publicado no: | Endocrinology |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7410368/ https://ncbi.nlm.nih.gov/pubmed/32603429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa102 |
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