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Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production

Evidence has mounted that insulin can be synthesized in various brain regions, including the hypothalamus. However, the distribution and functions of insulin-expressing cells in the hypothalamus remain elusive. Herein, we show that in the mouse hypothalamus, the perikarya of insulin-positive neurons...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Jaemeun, Kim, Kyungchan, Cho, Jae Hyun, Bae, Jin Young, O’Leary, Timothy P., Johnson, James D., Bae, Yong Chul, Kim, Eun-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455129/
https://ncbi.nlm.nih.gov/pubmed/32644973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135412
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