A positively selected FBN1 missense variant reduces height in Peruvians

On average, the Peruvian population is among the shortest in the world(1). Here we show that Native American ancestry is associated with reduced height in an ethnically diverse group of Peruvians, and identify a novel, population-specific, missense variant in FBN1 (E1297G) that is significantly asso...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Asgari, Samira, Luo, Yang, Akbari, Ali, Belbin, Gillian M., Li, Xinyi, Harris, Daniel N., Selig, Martin, Bartell, Eric, Calderon, Roger, Slowikowski, Kamil, Contreras, Carmen, Yataco, Rosa, Galea, Jerome T., Jimenez, Judith, Coit, Julia M., Farroñay, Chandel, Nazarian, Rosalynn M., O’Connor, Timothy D., Dietz, Harry C., Hirschhorn, Joel N., Guio, Heinner, Lecca, Leonid, Kenny, Eimear E., Freeman, Esther, Murray, Megan B., Raychaudhuri, Soumya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410362/
https://ncbi.nlm.nih.gov/pubmed/32499652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2302-0
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge