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Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5–15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection, presumably because they fail to mount an effective initial immune response. Here, in a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Luo, Yang, Suliman, Sara, Asgari, Samira, Amariuta, Tiffany, Baglaenko, Yuriy, Martínez-Bonet, Marta, Ishigaki, Kazuyoshi, Gutierrez-Arcelus, Maria, Calderon, Roger, Lecca, Leonid, León, Segundo R., Jimenez, Judith, Yataco, Rosa, Contreras, Carmen, Galea, Jerome T., Becerra, Mercedes, Nejentsev, Sergey, Nigrovic, Peter A., Moody, D. Branch, Murray, Megan B., Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704092/
https://ncbi.nlm.nih.gov/pubmed/31434886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11664-1
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